Receiving a kidney transplant is the preferred treatment for end-stage renal disease (ESRD). However, wait times to receive a transplant can be long, and the cost of medication to maintain the transplant is very high. Transplanted organs typically last around 10 years, if taken care of well. However, researchers at the Thomas E. Starzl Transplantation Institute at the University of Pittsburgh may have found the answer to prevent organ rejection. Fadi Lakkis, the scientific director at the transplantation institute, believed ideally, an organ transplant would last the rest of the patient’s life. Not only this, but the drugs that suppress the [...]

For several years, kidneys infected with Hepatitis C have been considered unfit for transplants due to the risk for transmission. However, with a new wave of antiviral medications shown to cure Hepatitis C, doctors at the University of Pennsylvania and Johns Hopkins University are planning to attempt transplants with kidneys from deceased Hepatitis C carriers. The patient who receives the kidney would then undergo a 12-week antiviral drug regimen to treat the disease. The trial’s leaders caution that the drugs won’t work for every participant, but argue the process has the potential to eliminate the waste that comes with the disposal [...]

A recent study conducted by the University of Cincinnati found that patient outcomes were almost identical for generic and brand-name versions of tacrolimus, a drug used post-transplant to reduce the risk of organ rejection. With more affordable generics now on the market, the study took a closer look at the outcomes of what have often been referred to as narrow therapeutic index medications. The study’s lead investigator Rita Alloway, PharmD (a research professor of medicine and director of transplant clinical research at University of Cincinnati’s Department of Internal Medicine) presented the study findings at the 2015 American Transplant Congress. The Food [...]